Petsoothicals Pro Flex

Petsoothicals ProFlex is a powdered product that is intended for animals that exhibit severe pain, stiffness, and immobility. It is a powdered supplement that can be administered with your animals food.

Dogs 0 to 29lbs - 1 heaping scoop, 30 to 59lbs - 2 heaping scoops, 60 to 89 - 3 heaping scoops, 90+ lbs - 4 heaping scoops.

Resveratrol is safe for long-term daily use, as it inhibits gene expression of the COX-2 enzyme without affecting the production of COX-1 enzymes and their gastro-protective byproduct prostaglandins. Rather than inhibiting active COX-1 and COX-2 enzymes circulating in the body, resveratrol inhibits the gene expression of COX-2 enzymes, thus reducing the level of this enzyme present in the body. Resveratrol inhibits a nuclear cofactor (NF-kappaB) that is required for gene expression of COX-2 enzymes, as well as many other pro-inflammatory compounds such as interleukins, tumor necrosis factor alpha, peroxidases, lipoxygenases and nitrous oxide synthases, but it does not affect the production of gastro-protective prostaglandins.