HeartGard Plus Chewables

For use in dogs to prevent canine heartworm disease by eliminating the tissue stage of heartworm larvae (Dirofilaria immitis) for a month (30 days) after infection and for the treatment and control of ascarids (Toxocara canis, Toxascaris leonina) and hookworms (Ancylostoma caninum, Unicinaria stenocephala, Ancylostoma braziliense).

Dosage: HeartGard Plus (ivermecterin/pyrantel) Chewables should be administered orally at monthly intervals at the recommended minimum dose level of 6 mcg of ivermecterin per kilogram (2.72 mcg/lb) and 5 mg of pyrantel (as pamoate salt) per kg (2.27 mg/lb) of body weight. The recommended dosing schedule for prevention of canine heartworm disease and for the control of ascarids and hookworms is as follows -up to 25lb 1 chewable per month color coding on foil backing and carton is blue26-50lb 1 chewable per month color coding on foil backing and carton is green51-100lb 1 chewable per month color coding on foil backing and carton is brownHeartGard Plus is recommended for dogs 6 weeks of age and older.For dogs over 100lb use the appropriate combination of these chewables.Administration: Remove only one chewable at a time from the foil back blister card. Return the card with the remaining chewables to its box to protect from light. Because most dogs find HeartGard Plus palatable, the product can be offered to the dog by hand. Alternatively, it may be added to a small amount of dog food. The chewable should be administered in a manner that encourages the dog tochew, rather than to swallow without chewing. Chewables may be broken into pieces and fed to dogs that normally swallow treats whole.Care should be taken that the dog consumes the complete dose, and treated animal should be observed for a few minutes after administration to ensure that part of the dose is not lost or rejected. If it is suspected that any of the dose has been lost, redosing is recommended.HeartGard Plus should be given at monthly intervals during the period of the year when mosquitoes (vectors), potentially carrying infective heartworm larvae, are active. The initial dose must be given within a month (30 days) after the dog's first exposure to mosquitoes. The final dose must be given within a month (30 days) after the dog's last exposure to mosquitoes.When replacing another heartworm preventive product in a heartworm disease prevention program, the first dose of HeartGard Plus must be given within a month (30 days) of the last dose of the former medication.If the interval between doses exceeds a month (30 days), the efficacy of ivermecterin can be reduced. Therefore, for optimal performance, the chewable must be given once a month on or about the same day of the month. If treatment is delayed, whether by a few days or many, immediate treatment with HeartGard Plus and resumption of the recommended dosing regimen will minimize the opportunity for the development of adult heartworms.Monthly treatment with HeartGard Plus also provides effective treatment and control os ascarids (T. canis, T leonina) and hookworms (A. canium, U stenocephala, A. braziliense). Clients should be advised of measures to be taken to prevent reinfection with intestinal parasites.Efficacy: Heartgard Plus chewables, given orally using the recommended dose and regimen, are effective against the tissue larval stage of D. immitis for a month (30 days) after infection and, as a result, prevent the development of the adult stage. Heartgard Plus Chewables are also effective against canine ascarids (T. canis, T leonina) and hookworms (A. caninum, U stenocephala, A. braziliense).

Prescription Drug policy: Prescription drugs can only be shipped upon receipt of an original script from a licensed veterinarian. FarmVet.com can accept an original prescription in one of the following ways: 1) the original prescription may be mailed to: 1041 Sneed Road, Franklin, TN 37204 2) A licensed veterinarian may fax the prescription to 615-574-6057. The fax must originate from the veterinarians office 3) A licensed veterinarian can call your prescription into the pharmacy 615-277-5602. Voicemail is acceptable. Prescriptions are refillable, if indicated by your vet, for up to one year from the original date. At the end of one year prescriptions must be updated. Written prescriptions must include the veterinarian's license number, telephone number, and address. Federal (U.S.A.) law restricts the use of Rx drugs to use by, or on the order of a licensed veterinarian. Prescription drug forms available upon request.

Precautions: store at controlled room temperature of 59-86F (15-30 C). Protect product from light.Federal law restricts this drug to use by or on the order of a licensed veterinarian. All dogs should be tested for existing heartworm infection before starting treatment with HeartGard Plus which is not effective against adult D. immitis. Infected dogs must be treated to remove adult heartworms and microfilarie before initiating a program with HeartGard Plus. While some microfilariae may be killed by the ivermecterin in HeartGard Plus at the recommended dose level, HeartGard Plus is not effective for microfilariae clearance. A mild hypersensitivity-type reaction, presumably due to dead or dying microfilariae and particularly involving a transient diarrhea, has been observed in clinical trials with ivermecterin alone after treatment of some dogs that have circulating microfilariae.Keep this and all drugs out of reach of children.In case of ingestion by humans, clients should be advised to contact a physician immediately. Physicians may contact a Poison Control Center for advice concerning cases of ingestion by humans.In clinical field trials with HeartGard Plus, vomiting or diarrhea within 24 hours of dosing was rarely observed (1.1% of administered doses). The following adverse reactions have been reported following the use of HeartGard: depression/lethargy, vomitting, anorexia,diarrhea, mydriasis, ataxia, staggering, convulsions, and hypersalivation.