Prednisolone Syrup

DVM Resources

ITEM IS CURRENTLY ON MANUFACTURER BACKORDER. PLEASE CALL OR EMAIL FOR ESTIMATED DATE OF AVAILABILITY: 888.837.3626. Lessens swelling and pain caused by inflammation. Prednisolone is given systemically to decrease inflammatory and immune responses.


Size 16 oz

Attribute 15 mg/5 ml

Chronic or inappropriate use of corticosteroids including prednisolone can cause life-threatening hormonal and metabolic changes, specifically iatrogenic Cushing's Disease or Addison's Disease. Corticosteroids such as prednisolone should not be used in animals with systemic fungal infection. Adverse effects due to corticosteroid treatment usually occur with long-term administration of the drug, especially when high doses are used. If possible, the longer- acting corticosteroids should be avoided for long-term therapy. 

Prednisolone is considered a shorter-acting corticosteroid. Alternate-day therapy with short-acting preparations is preferred. Animals that have received long-term therapy should be withdrawn slowly by tapering the dosage and prolonging the interval between doses. 

Corticosteroids suppress immune response. Animals receiving systemic corticosteroids may be more susceptible to bacterial or viral infections. Systemic corticosteroids can mask signs of infection, such as an elevated temperature. Corticosteroids can cause or worsen gastric ulcers. 

Corticosteroids should be avoided or used very carefully in young animals both because of immune suppression and the risk of GI ulcers in this population. 

Corticosteroids have been implicated as a cause of laminitis in horses and ponies. Some corticosteroids are thought to be more likely to cause laminitis than others and prednisolone historically has not been considered to be in the higher-risk category. Pony breeds and horses with pituitary pars intermedia dysfunction or metabolic syndrome may be more susceptible to developing laminitis. 

Corticosteroids should be avoided during pregnancy and lactation unless the benefits outweigh the risks. Large doses in early pregnancy may be teratogenic. Corticosteroids will cross into maternal milk.

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