BO-SE Injection (Selenium and Vitamin E)

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BO-SE Injection (Selenium and Vitamin E) from Merck is recommended for the prevention and treatment of white muscle disease (Selenium-Tocopherol Deficiency) syndrome in calves, lambs, and ewes. Clinical signs are: stiffness and lameness, diarrhea and unthriftiness, pulmonary distress and/or cardiac arrest.

In sows and weanling pigs, as an aid in the prevention and treatment of diseases associated with Selenium-Tocopherol deficiency, such as hepatic necrosis, mulberry heart disease, and white muscle disease. Where known deficiencies of selenium and/or vitamin E exist, it is advisable, from the prevention and control standpoint, to inject the sow during the last week of pregnancy.


  • Prevention and treatment of white muscle disease
  • For use in calves, lambs, ewes, sows, and weanling pigs
  • Consult with a veterinarian for exact dosing instructions


Consult with a veterinarian for exact dosing instructions.

Calves: 2.5-3.75 mL per 100 pounds of body weight depending on the severity of the condition and the geographical area. Lambs 2 weeks of age and older: 1 mL per 40 pounds of body weight (minimum, 1 mL). Ewes: 2.5 mL per 100 pounds of body weight. Sows: 1 mL per 40 pounds of body weight. Weanling pigs: 1 mL per 40 pounds of body weight (minimum, 1 mL). Not for use in newborn pigs.


Prescription Drug Policy:

Prescriptions CAN NOT be shipped to North Carolina, Hawaii or Alaska at this time.

Prescription drugs can only be shipped upon receipt of an original prescription from a licensed veterinarian. FarmVet can accept an original prescription in one of the following ways:
  • The original prescription may be mailed to:
    1254 Old Hillsboro Rd, Franklin,TN 37069 
  • A licensed veterinarian may fax the Rx to 615-370-8502.
    The fax must originate from the veterinarian's office.
  • A licensed veterinarian can call & leave a voicemail with your prescription information with our pharmacy at 615-277-5602.

Prescriptions are non-refundable. Prescriptions are refillable if indicated by your vet, for up to one year from the original date. At the end of one year, prescriptions must be updated. Written prescriptions must include the veterinarian's license number, telephone number, and address. Federal law restricts the use of Rx drugs to use by, or on the order of a licensed veterinarian.


Anaphylactoid reactions, some of which have been fatal, have been reported in animals administered BO-SE Injection. Signs include excitement, sweating, trembling, ataxia, respiratory distress, and cardiac dysfunction. Selenium-Vitamin E preparations can be toxic when improperly administered. Store at 25°C (77°F) with excursions permitted between 23 - 32°C (74 - 89°F). Occasionally, the product may segregate in two phases or may become turbid. Do not use product that has exhibited phase separation or turbidity.

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