Marquis Paste

Marquis from Boehringer Ingelheim is designated for the treatment of Equine Protozoal Myeloencephalitis (EPM) caused by Sarcocystis neurons.

Marquis Paste is supplied in a ready-to-use syringe that contains 127 grams of paste. Each gram of paste contains 150 mg of ponazuril (15% w/w). Marquis is designed to be administered orally.

The plunger contains a dosage ring calibrated for a dose rate of 5 mg/kg (2.27 mg/lb) body weight and marked for horse weight from 600 to 1,200 lbs (272 to 544 kg). Each paste comes with a re-usable plunger.  

Marquis (ponazuril) is to be used at a dose of 5 mg/kg (2.27 mg/lb) body weight once daily for a period of 7 days.

Directions for use: Before administration, the syringe barrel and plunger require assembly. Ensure plunger is clean and dry. 
Step 1) End cap must be on syringe barrel when inserting plunger. Step 2) Carefully insert reusable plunger into base of syringe barrel until it snaps into place, then remove end cap and gently apply pressure to the plunger until paste is seen at the tip of the syringe barrel. 
Step 3) Return end cap to tip of paste syringe.

Prescription Drug Policy:

Prescriptions CAN NOT be shipped to North Carolina, Hawaii or Alaska at this time.

Prescription drugs can only be shipped upon receipt of an original prescription from a licensed veterinarian. FarmVet can accept an original prescription in one of the following ways:
 

• The original prescription may be mailed to:
  1254 Old Hillsboro Rd, Franklin,TN 37069 
• A licensed veterinarian may fax the Rx to 615-370-8502.
  The fax must originate from the veterinarian's office.
• A licensed veterinarian can call & leave a voicemail with your prescription information with our pharmacy at 615-505-3136.

Prescriptions are non-refundable. Prescriptions are refillable if indicated by your vet, for up to one year from the original date. At the end of one year, prescriptions must be updated. Written prescriptions must include the veterinarian's license number, telephone number, and address. Federal law restricts the use of Rx drugs to use by or on the order of a licensed veterinarian.

Prior to treatment, EPM should be distinguished from other diseases that may cause ataxia in horses. Injuries or lameness may also complicate the evaluation of an animal with EPM. In most instances, ataxia due to EPM is asymmetrical and affects the hind limbs.

Clinicians should recognize that clearance of the parasite by ponazuril may not completely resolve the clinical signs attributed to the natural progression of the disease. The prognosis for animals treated for EPM may be dependent upon the severity of disease and the duration of the infection prior to treatment. The safe use of Marquis (ponazuril) in horses used for breeding purposes, during pregnancy, or in lactating mares, has not been evaluated. The safety of Marquis (ponazuril) with concomitant therapies in horses has not been evaluated.